Description

Methyl 4-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Benzoate is a high-value fluorinated aromatic ester building block, prized for its unique structural motifs that enable precise molecular tuning in advanced synthesis. Its core value lies in providing a versatile scaffold for introducing both fluorine and trifluoromethyl groups, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and thermal stability.
• Polymer & Specialty Chemicals: Incorporated as a monomer or modifier to create high-performance polymers with enhanced chemical resistance, low surface energy, and specific optical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring novel fluorination chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 4-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Benzoate
CAS No.	1365273-05-7
Molecular Formula	C15H10F4O2
Molecular Weight	298.24 g/mol
Synonyms	Methyl 4-(2-Fluoro-3-(trifluoromethyl)phenyl)benzoate; Benzoic acid, 4-[2-fluoro-3-(trifluoromethyl)phenyl]-, methyl ester; 2-Fluoro-3-(trifluoromethyl)phenyl 4-benzoate methyl ester; Methyl 4-(2-fluoro-α,α,α-trifluoro-m-tolyl)benzoate; 4-(2-Fluoro-3-trifluoromethylphenyl)benzoic acid methyl ester; Methyl p-[2-fluoro-3-(trifluoromethyl)phenyl]benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Benzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality management systems for advanced chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.