Description

2-Fluoro-4-(2-Nitrophenyl)Benzoic Acid is a high-purity fluorinated aromatic building block with a nitrophenyl substituent, designed for advanced synthetic chemistry. This compound is valued for its role as a key intermediate in the development of complex organic molecules, particularly in pharmaceutical research and agrochemical discovery. It is essential for R&D chemists and process development scientists working in life sciences, material science, and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring fluorinated aromatic scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom and nitro group can enhance biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to construct complex biaryl systems for various research applications.
• Chemical Biology Probe Development: Utilized to create fluorescent tags, photoaffinity labels, or other molecular probes for studying biological systems and mechanisms.

Basic Information

Product Name	2-Fluoro-4-(2-Nitrophenyl)Benzoic Acid
CAS No.	1365272-19-0
Molecular Formula	C13H8FNO4
Molecular Weight	261.21 g/mol
Synonyms	2-Fluoro-4-(2-nitrophenyl)benzoic acid; 4-(2-Nitrophenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-2-nitro-; 2'-Fluoro-2-nitro[1,1'-biphenyl]-2-carboxylic acid; 2-Fluoro-4-(o-nitrophenyl)benzoic acid; 2-Fluoro-4-(2-nitro-phenyl)-benzoic acid; 1365272-19-0
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(2-Nitrophenyl)Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.