Description

Methyl 2-Fluoro-4-(3-Fluoro-5-Methoxyphenyl)Benzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its value lies in its precise molecular architecture, featuring strategically placed fluorine and methoxy substituents that are crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery programs, particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity, stability, and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with tailored thermal, optical, or surface properties.
• Chemical Biology Probe Development: Utilized in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring high-fidelity fluorinated intermediates.

Basic Information

Product Name	Methyl 2-Fluoro-4-(3-Fluoro-5-Methoxyphenyl)Benzoate
CAS No.	1365272-01-0
Molecular Formula	C15H12F2O3
Molecular Weight	278.25 g/mol
Synonyms	2-Fluoro-4-(3-fluoro-5-methoxyphenyl)benzoic acid methyl ester; Methyl 2-fluoro-4-[3-fluoro-5-(methoxy)phenyl]benzoate; Benzoic acid, 2-fluoro-4-(3-fluoro-5-methoxyphenyl)-, methyl ester; 1365272-01-0; 2-Fluoro-4-(3-fluoro-5-methoxyphenyl)methyl benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Fluoro-4-(3-Fluoro-5-Methoxyphenyl)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up work. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.