Description

Methyl 3-(4-Cyanophenyl)-5-Fluorobenzoate CAS NO 1365271-88-0 is a high-purity fluorinated aromatic ester building block, serving as a critical intermediate in advanced organic synthesis. Its molecular structure, featuring both cyano and fluoro substituents, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by pharmaceutical and agrochemical R&D sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular core of liquid crystals and organic light-emitting diode (OLED) compounds.
• Polymer Modification: Employed to introduce fluorinated and cyano-functionalized side chains into specialty polymers, improving their chemical resistance and thermal properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring novel carbon-carbon and carbon-heteroatom bond-forming reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	Methyl 3-(4-Cyanophenyl)-5-Fluorobenzoate
CAS No.	1365271-88-0
Molecular Formula	C15H10FNO2
Molecular Weight	255.25 g/mol
Synonyms	Methyl 5-Fluoro-3-(4-cyanophenyl)benzoate; 3-(4-Cyanophenyl)-5-fluorobenzoic Acid Methyl Ester; 5-Fluoro-3'-(4-cyanophenyl)benzoic Acid Methyl Ester; Benzoic acid, 3-(4-cyanophenyl)-5-fluoro-, methyl ester; Methyl 3-(4-cyanophenyl)-5-fluorobenzoate; Methyl 5-fluoro-[1,1'-biphenyl]-3-carboxylate-4'-carbonitrile
EINECS	Contact for details

Quality Control

Our Methyl 3-(4-Cyanophenyl)-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container tightly sealed under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.