Description

3-Fluoro-5-(3-Fluoropyridin-2-Yl)Benzoic Acid is a high-value, multi-functional aromatic building block featuring a benzoic acid core substituted with fluorine atoms and a fluoropyridinyl moiety. This compound is critical for medicinal chemistry research and development, offering precise structural control for modulating the pharmacokinetic and binding properties of new chemical entities. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Material Science: Serves as a precursor for creating specialized ligands in catalysis and as a building block for advanced organic electronic materials.
• Chemical Biology Probe Development: Employed to create fluorescent or affinity tags for studying protein-ligand interactions and cellular processes.

Basic Information

Product Name	3-Fluoro-5-(3-Fluoropyridin-2-Yl)Benzoic Acid
CAS No.	1365271-83-5
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	2,3'-Difluoro-5'-carboxy-2,3-bipyridine; 3-Fluoro-5-(3-fluoropyridin-2-yl)benzoic acid; 2-(3-Fluoro-5-carboxyphenyl)-3-fluoropyridine; 5-(3-Fluoropyridin-2-yl)-3-fluorobenzoic acid; 1365271-83-5; 3-Fluoro-5-(3-fluoro-2-pyridinyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-5-(3-Fluoropyridin-2-Yl)Benzoic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for reliable supply into regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.