Description

Benzoic Acid, 2,5-Difluoro-4-Methyl-, Methyl Ester is a high-purity fluorinated aromatic ester, serving as a critical advanced pharmaceutical intermediate and custom synthesis building block. Its unique difluoro-methyl benzoate structure makes it invaluable for introducing specific steric and electronic properties into target molecules. This compound is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRAM) for producing specialized fine chemicals and complex organic molecules.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing side chains into polymers, altering their solubility, thermal stability, and surface properties.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodology development and exploring new fluorination reactions.

Basic Information

Product Name	Benzoic Acid, 2,5-Difluoro-4-Methyl-, Methyl Ester
CAS No.	1355488-71-9
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2,5-Difluoro-4-methylbenzoic acid methyl ester; Methyl 2,5-difluoro-4-methylbenzoate; 4-Methyl-2,5-difluorobenzoic acid methyl ester; 2,5-Difluoro-p-toluic acid methyl ester; Methyl 2,5-difluoro-4-methylbenzenecarboxylate; 1355488-71-9; Benzoic acid, 2,5-difluoro-4-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2,5-Difluoro-4-Methyl-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent batch-to-batch performance. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, supporting compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.