Description

Methyl 2-Fluoro-5-(3-Nitrophenyl)Benzoate is a high-purity, synthetically valuable fluorinated aromatic ester building block. This compound is critical for advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated aromatic cores in electronic and optoelectronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of reactive functional groups.
• Chemical Biology Probes: Utilized in the design of fluorophore-labeled probes and enzyme inhibitors for biochemical research.
• Polymer Modification: Incorporated as a monomer or modifier to impart specific properties like chemical resistance or altered refractive index to advanced polymers.

Basic Information

Product Name	Methyl 2-Fluoro-5-(3-Nitrophenyl)Benzoate
CAS No.	1355248-04-2
Molecular Formula	C14H10FNO4
Molecular Weight	275.24 g/mol
Synonyms	Methyl 2-Fluoro-5-(3-nitrophenyl)benzoate; 2-Fluoro-5-(3-nitrophenyl)benzoic Acid Methyl Ester; Benzoic acid, 2-fluoro-5-(3-nitrophenyl)-, methyl ester; Methyl 2-fluoro-5-[3-nitrophenyl]benzoate; 3'-Nitro-2-fluoro-5'-methylbenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Fluoro-5-(3-Nitrophenyl)Benzoate is manufactured and tested under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles via HPLC, NMR, and MS is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.