Description

Methyl 3-Bromo-5-Chloro-2-Fluorobenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. Its value lies in providing a versatile, multi-halogenated scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the halogenated benzoate structure for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions and asymmetric catalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers and liquid crystals, where fluorine substitution modifies material properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated aromatic intermediates.

Basic Information

Product Name	Methyl 3-Bromo-5-Chloro-2-Fluorobenzoate
CAS No.	1353575-32-2
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	3-Bromo-5-chloro-2-fluorobenzoic acid methyl ester; Methyl 3-bromo-5-chloro-2-fluorobenzoate; Benzoic acid, 3-bromo-5-chloro-2-fluoro-, methyl ester; 2-Fluoro-3-bromo-5-chlorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-5-Chloro-2-Fluorobenzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We maintain ISO 9001 certified quality management systems and can provide material suitable for research and development under current Good Manufacturing Practice (cGMP) guidelines for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.