Description

Ortho-Nitroveratryloxycarbonyl-5-Carboxy-Q-Rhodamine is a specialized, photolabile protected derivative of the Q-Rhodamine fluorophore. This compound is engineered for critical applications in advanced bioconjugation and labeling strategies, where controlled release of the active fluorophore is required. It is an essential reagent for researchers and manufacturers in the fields of proteomics, bioassay development, and diagnostic probe synthesis, enabling the creation of sensitive and specific detection systems.

Application

• Synthesis of caged fluorescent probes for biological imaging and sensing.
• Phototriggered bioconjugation strategies for labeling proteins, peptides, and antibodies.
• Development of advanced fluorescent substrates for enzyme activity assays (e.g., protease, nuclease).
• Preparation of high-sensitivity diagnostic reagents for clinical and research immunoassays.
• Building block for super-resolution microscopy and single-molecule tracking studies.
• Chemical biology research involving spatiotemporally controlled activation of signaling molecules.

Basic Information

Product Name	Ortho-Nitroveratryloxycarbonyl-5-Carboxy-Q-Rhodamine
CAS No.	1352809-04-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NVOC-Q-Rhodamine-5-COOH; o-Nitroveratryloxycarbonyl-Q-Rhodamine-5-carboxylic acid; 5-Carboxy-Q-Rhodamine NVOC ester; Photocaged Q-Rhodamine acid; Q-Rhodamine, 5-carboxy-, 2-nitroveratryloxycarbonyl derivative; QRH-NVOC-5-COOH
EINECS	Contact for details

Quality Control

Our Ortho-Nitroveratryloxycarbonyl-5-Carboxy-Q-Rhodamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for reproducible research and manufacturing outcomes. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	Red to dark red powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.