Description

Benzoic Acid, 6-Bromo-2-Fluoro-3-(Trifluoromethyl)-, Methyl Ester is a high-value, multi-functionalized aromatic building block designed for advanced synthetic chemistry. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogen and trifluoromethyl substitution pattern enables precise structural modifications. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the fluorine and bromine substituents.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where the trifluoromethyl group can impart desirable thermal and chemical resistance properties.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Benzoic Acid, 6-Bromo-2-Fluoro-3-(Trifluoromethyl)-, Methyl Ester
CAS No.	1352718-55-8
Molecular Formula	C10H5BrF4O2
Molecular Weight	313.05 g/mol
Synonyms	Methyl 6-Bromo-2-fluoro-3-(trifluoromethyl)benzoate; 6-Bromo-2-fluoro-3-(trifluoromethyl)benzoic acid methyl ester; 2-Fluoro-6-bromo-α,α,α-trifluoro-m-toluic acid methyl ester; Benzoic acid, 6-bromo-2-fluoro-3-(trifluoromethyl)-, methyl ester; Methyl 2-fluoro-6-bromo-3-(trifluoromethyl)benzoate; 1352718-55-8
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 6-Bromo-2-Fluoro-3-(Trifluoromethyl)-, Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation, with each shipment. Certificates of Analysis (COA) are available upon request, and we support custom synthesis to meet specific purity or impurity profile requirements for advanced R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.