Description

Methyl 3-(2-Cyanophenyl)-5-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both cyano and fluoro substituents, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and material science.
• Fluorescent Dye and Sensor Synthesis: The conjugated system is applicable in the preparation of advanced organic materials for optoelectronic applications.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions and fluorination chemistry within R&D laboratories.

Basic Information

Product Name	Methyl 3-(2-Cyanophenyl)-5-Fluorobenzoate
CAS No.	1352318-48-9
Molecular Formula	C15H10FNO2
Molecular Weight	255.25 g/mol
Synonyms	Methyl 5-Fluoro-3-(2-cyanophenyl)benzoate; 3-(2-Cyanophenyl)-5-fluorobenzoic Acid Methyl Ester; 5-Fluoro-3-(2-cyanophenyl)benzoic Acid Methyl Ester; Benzoic acid, 3-(2-cyanophenyl)-5-fluoro-, methyl ester; Methyl 5-fluoro-[1,1'-biphenyl]-3-carboxylate-2'-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(2-Cyanophenyl)-5-Fluorobenzoate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with ICH guidelines for impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.