Description

2-Fluoro-4-(4-Nitrophenyl)Benzoic Acid is a high-value fluorinated aromatic building block with a nitrophenyl substituent, offering unique electronic and steric properties for advanced synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials that require precise molecular tuning. It is primarily utilized in pharmaceutical R&D, agrochemical discovery, and as a key intermediate in the synthesis of liquid crystal and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorine atom and nitro group enhance biological activity and stability.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and other functional materials due to its conjugated system and polar groups.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a precursor for further functionalization to create diverse chemical libraries.
• Dye & Pigment Intermediate: The nitrophenyl and benzoic acid moieties make it a potential precursor for specialized dyes and colorants.

Basic Information

Product Name	2-Fluoro-4-(4-Nitrophenyl)Benzoic Acid
CAS No.	1352318-47-8
Molecular Formula	C₁₃H₈FNO₄
Molecular Weight	261.21 g/mol
Synonyms	4'-Nitro-2-fluorobiphenyl-4-carboxylic Acid; 2-Fluoro-4'-(4-nitrophenyl)benzoic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 2-fluoro-4'-nitro-; 2-Fluoro-4-(4-nitrophenyl)benzoic Acid; 4-(4-Nitrophenyl)-2-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4-Nitrophenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.