Description

2-Fluoro-5-(4-Nitrophenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorinated aromatic core can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemical Modification: Acts as a monomer or modifier to introduce specific functional groups into polymers, influencing their thermal stability, solubility, and chemical resistance.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and the development of new fluorination techniques.
• Dye & Pigment Intermediate: Potential precursor in the synthesis of specialized dyes and pigments where nitro and carboxylic acid functionalities are required.

Basic Information

Product Name	2-Fluoro-5-(4-Nitrophenyl)Benzoic Acid
CAS No.	1352317-91-9
Molecular Formula	C13H8FNO4
Molecular Weight	261.21 g/mol
Synonyms	5-(4-Nitrophenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-5-nitro-; 2-Fluoro-5-(4-nitrophenyl)benzoic acid; 2'-Fluoro-5-nitro[1,1'-biphenyl]-2-carboxylic acid; 2-Fluoro-5-(p-nitrophenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(4-Nitrophenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.