Description

3-(2-Cyanophenyl)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both cyano and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its electron-withdrawing groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	3-(2-Cyanophenyl)-5-Fluorobenzoic Acid
CAS No.	1352317-82-8
Molecular Formula	C14H8FNO2
Molecular Weight	241.22 g/mol
Synonyms	5-Fluoro-3-(2-cyanophenyl)benzoic Acid; 3-(2-Cyanophenyl)-5-fluorobenzoic Acid; 2'-Cyano-5-fluorobiphenyl-3-carboxylic Acid; 5-Fluoro-[1,1'-biphenyl]-3-carboxylic acid, 2'-cyano-; Benzoic acid, 3-(2-cyanophenyl)-5-fluoro-; 1352317-82-8
EINECS	Contact for details

Quality Control

Our 3-(2-Cyanophenyl)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with detailed chromatograms and spectra are provided for every shipment, supporting regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.