Description

3-Chloro-2,4,5,6-Tetrafluorobenzotrichloride is a highly functionalized halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the combination of reactive trichloromethyl and chloro-fluoro substitution patterns, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring a multi-halogenated benzene core for further functionalization.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine and chlorine atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Employed to introduce halogenated aromatic units into polymer chains, enhancing properties like flame retardancy, chemical resistance, and thermal stability.
• Cross-Coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of reactive chlorine atoms.
• Fluorinated Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Item	Detail
Product Name	3-Chloro-2,4,5,6-Tetrafluorobenzotrichloride
CAS No.	1350637-05-6
Molecular Formula	C7Cl4F4
Molecular Weight	315.78 g/mol
Synonyms	Benzene, 1,2,3,4-tetrafluoro-5-(trichloromethyl)-, 6-chloro-; 5-(Trichloromethyl)-2,3,4,6-tetrafluorobenzoyl chloride (related); 3-Chloro-2,4,5,6-tetrafluoro-α,α,α-trichlorotoluene; 2,3,4,6-Tetrafluoro-5-(trichloromethyl)chlorobenzene; 3-Chloro-α,α,α,2,4,5,6-heptachlorotoluene (incorrect but common search); TCTFB (abbreviation); Perfluorinated Benzotrichloride Derivative
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2,4,5,6-Tetrafluorobenzotrichloride adheres to a stringent quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency critical for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.