Description

3-Fluoro-4-(Oxetan-3-Yloxy)Benzoic Acid is a high-value pharmaceutical intermediate and building block characterized by its benzoic acid core functionalized with both fluorine and an oxetane ether group. This unique molecular architecture makes it a critical synthon for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in SAR (Structure-Activity Relationship) studies and lead optimization due to the desirable physicochemical properties imparted by the fluorine and oxetane motifs.
• Agrochemical Synthesis: Intermediate in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from gram to kilogram.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in organic synthesis and new material development.

Basic Information

Product Name	3-Fluoro-4-(Oxetan-3-Yloxy)Benzoic Acid
CAS No.	1346498-50-7
Molecular Formula	C10H9FO4
Molecular Weight	212.17 g/mol
Synonyms	3-Fluoro-4-(3-oxetanyloxy)benzoic acid; 4-(Oxetan-3-yloxy)-3-fluorobenzoic acid; Benzoic acid, 3-fluoro-4-(3-oxetanyloxy)-; 1346498-50-7; 3-Fluoro-4-(oxetan-3-yloxy)benzoic acid; 3-Fluoro-4-(oxetane-3-yloxy)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Oxetan-3-Yloxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.