Description

5-[4-(Carboxymethyl)Phenyl]-2-Fluorobenzoic Acid is a high-purity, multifunctional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorobenzoic acid and a carboxymethylphenyl moiety, makes it an exceptionally versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors, where precise molecular architecture is paramount for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom and carboxylic acid groups contribute to bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating sophisticated organic semiconductors and liquid crystal compounds used in display technologies.
• Polymer Modification: Employed as a monomer or cross-linking agent to introduce fluorinated and carboxylic acid functionalities into polymers, enhancing their chemical resistance and adhesion properties.
• Metal-Organic Framework (MOF) Synthesis: Acts as a functionalized organic linker in the construction of porous MOFs for gas storage, separation, and catalysis applications.
• Peptide Mimetics & Conjugation: Utilized in medicinal chemistry for the design of peptide analogs and for bioconjugation strategies, leveraging its carboxylic acid groups for amide bond formation.

Basic Information

Product Name	5-[4-(Carboxymethyl)Phenyl]-2-Fluorobenzoic Acid
CAS No.	1345472-27-6
Molecular Formula	C16H11FO4
Molecular Weight	286.26 g/mol
Synonyms	2-Fluoro-5-[4-(carboxymethyl)phenyl]benzoic acid; 4'-(Carboxymethyl)-[1,1'-biphenyl]-2-fluoro-4-carboxylic acid; 5-(4-Carboxymethylphenyl)-2-fluorobenzoic acid; Biphenyl-2-fluoro-4,4'-dicarboxylic acid, 4'-methyl ester (related); [1,1'-Biphenyl]-4-acetic acid, 2'-fluoro-4'-carboxy-; FCBA Intermediate
EINECS	Contact for details

Quality Control

Every batch of 5-[4-(Carboxymethyl)Phenyl]-2-Fluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.