Description

3-(2-Acetylphenyl)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative characterized by its acetylphenyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers for developing novel active compounds and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Building block for developing new-generation fluorinated pesticides and herbicides with enhanced efficacy.
• Material Science: Used in the synthesis of specialty polymers and liquid crystal materials requiring specific fluorinated aromatic components.
• Organic Synthesis: Versatile reagent for constructing complex molecular architectures via reactions at the carboxylic acid or ketone functional groups.
• Chemical Biology: Probe or linker molecule in bioconjugation and the development of chemical tools for biological studies.

Basic Information

Product Name	3-(2-Acetylphenyl)-5-Fluorobenzoic Acid
CAS No.	1345471-99-9
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	5-Fluoro-3-(2-acetylphenyl)benzoic Acid; 3-(2-Acetylphenyl)-5-fluorobenzoic Acid; 2-Acetyl-5'-fluorobiphenyl-3-carboxylic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 2-acetyl-5'-fluoro-; 5'-Fluoro-2-acetyl[1,1'-biphenyl]-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Acetylphenyl)-5-Fluorobenzoic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent screening, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.