Description

5-(2-Acetylphenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both acetyl and fluorine substituents, makes it a valuable intermediate for constructing complex pharmacophores and functional materials. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic systems.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Building block for advanced polymers, liquid crystals, and organic electronic materials due to its rigid, functionalized structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	5-(2-Acetylphenyl)-2-Fluorobenzoic Acid
CAS No.	1345471-80-8
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	2'-Acetyl-2-fluorobiphenyl-5-carboxylic Acid; 2-Fluoro-5-(2-acetylphenyl)benzoic Acid; 5-(2-Acetylphenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-5-carboxylic acid, 2'-acetyl-2-fluoro-; 2-Fluoro-5-(2-acetylphenyl)benzoic acid; 2'-Acetyl-2-fluoro[1,1'-biphenyl]-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Acetylphenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.