Description

5-(2-Cyanophenyl)-2-Fluorobenzoic Acid is a high-purity, multifunctional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique molecular architecture, which combines a fluorinated benzoic acid core with an ortho-cyanophenyl substituent, offering versatile reactivity for constructing complex molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a critical scaffold for developing new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and materials science, where the cyano and carboxylic acid groups allow for precise functionalization.
• Fluorinated Compound Library: An essential building block for creating diverse fluorinated compound libraries used in high-throughput screening for drug discovery.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and advanced materials, where its aromatic and functional groups contribute to thermal stability and specific material properties.

Basic Information

Product Name	5-(2-Cyanophenyl)-2-Fluorobenzoic Acid
CAS No.	1345471-31-9
Molecular Formula	C14H8FNO2
Molecular Weight	241.22 g/mol
Synonyms	2-Fluoro-5-(2-cyanophenyl)benzoic Acid; 5-(2-Cyanophenyl)-2-fluorobenzoic Acid; 2'-Cyano-2-fluoro[1,1'-biphenyl]-5-carboxylic Acid; [1,1'-Biphenyl]-5-carboxylic acid, 2'-cyano-2-fluoro-; 2-Fluoro-5-(o-cyanophenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 5-(2-Cyanophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.