Description

4-(Cyclopropylmethoxy)-3,5-Difluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the cyclopropylmethoxy ether and difluoro substitution pattern, which is instrumental for modulating the physicochemical properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients where such specific fluorinated scaffolds are required.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors or GPCR modulators.
• Agrochemical Synthesis: Used in the construction of advanced herbicides or fungicides, where the fluorine atoms and ether linkage contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers or liquid crystals, leveraging its aromatic and fluorinated structure.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of bioactive compounds for metabolic or binding studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in multi-step custom synthesis projects.

Basic Information

Product Name	4-(Cyclopropylmethoxy)-3,5-Difluorobenzoic Acid
CAS No.	1343436-42-9
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	3,5-Difluoro-4-(cyclopropylmethoxy)benzoic Acid; Benzoic acid, 3,5-difluoro-4-(cyclopropylmethoxy)-; 4-Cyclopropylmethoxy-3,5-difluorobenzoic Acid; 3,5-Difluoro-4-(cyclopropyloxymethyl)benzoic Acid; 4-(Cyclopropylmethoxy)-3,5-difluorobenzoic acid; CP-MO-DFBA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 4-(Cyclopropylmethoxy)-3,5-Difluorobenzoic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.