Description

2-(4-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Acetic Acid is a high-value trifluoromethylated pyrazole derivative, a versatile building block prized for its ability to impart unique physicochemical properties to advanced molecules. Its core value lies in serving as a critical synthetic intermediate for developing novel active ingredients in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers in medicinal chemistry, crop protection, and advanced material science who require reliable, high-purity intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic disorders, inflammation, and central nervous system (CNS) diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a functionalized backbone for creating novel ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-(4-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Acetic Acid
CAS No.	1341347-35-0
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	2-[4-(Trifluoromethyl)-1H-pyrazol-1-yl]acetic acid; 2-(4-Trifluoromethyl-1H-pyrazol-1-yl)acetic Acid; 1H-Pyrazole-1-acetic acid, 4-(trifluoromethyl)-; (4-Trifluoromethyl-1-pyrazolyl)acetic acid; 2-(4-Trifluoromethylpyrazol-1-yl)acetic Acid; 2-(4-Trifluoromethyl-1H-pyrazol-1-yl)ethanoic acid; 1341347-35-0; 2-(4-(Trifluoromethyl)-1H-pyrazol-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.