Description

4-Ethoxy-2-Trifluoromethylbenzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the ethoxy substituent, which enables precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a critical intermediate in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance, low surface energy, or altered refractive index to specialty polymers.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to construct complex, fluorinated molecular architectures for various R&D applications.
• Chemical Research & Development: A valuable reagent for academic and industrial laboratories exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	4-Ethoxy-2-Trifluoromethylbenzoic Acid
CAS No.	1340229-02-8
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	2-Trifluoromethyl-4-ethoxybenzoic Acid; 4-Ethoxy-2-(trifluoromethyl)benzoic Acid; Benzoic acid, 4-ethoxy-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-ethoxybenzoic Acid; 4-Ethoxy-α,α,α-trifluoro-o-toluic Acid
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2-Trifluoromethylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.