Description

Methyl 3-(4-Aminophenyl)-5-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, distinguished by its reactive amine and ester functional groups. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, offering a versatile scaffold for further chemical modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials, where its aromatic and fluorinated structure contributes to desired electronic and optical properties.
• Polymer Modification: Acts as a monomer or functionalization agent for creating specialty polymers with specific thermal, chemical, or surface characteristics.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating libraries of novel chemical entities for screening.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and organic pigments, where the amine group allows for coupling reactions.

Basic Information

Product Name	Methyl 3-(4-Aminophenyl)-5-Fluorobenzoate
CAS No.	1334499-98-7
Molecular Formula	C14H12FNO2
Molecular Weight	245.25 g/mol
Synonyms	5-Fluoro-3-(4-aminophenyl)benzoic acid methyl ester; Methyl 5-fluoro-3-(4-aminophenyl)benzoate; 3-(4-Aminophenyl)-5-fluorobenzoic acid methyl ester; Benzoic acid, 5-fluoro-3-(4-aminophenyl)-, methyl ester; 1334499-98-7; MFCD31811862
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(4-Aminophenyl)-5-Fluorobenzoate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development and commercial projects requiring consistency from milligram to kilogram scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.