Description

4-[(1-Carboxy-1-Methylethyl)Amino]-2-Fluorobenzoic Acid is a high-purity, fluorinated benzoic acid derivative serving as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorine atom and a protected amino acid moiety, enabling precise modifications in complex molecule construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients where fluorination is a key strategy to modulate bioactivity, metabolic stability, and membrane permeability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides where the fluorine substituent enhances biological activity and environmental stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocycles and functionalized aromatic compounds in medicinal and process chemistry.
• Fluorine Chemistry Research: An important compound for studying structure-activity relationships (SAR) and the effects of fluorination on molecular properties in academic and industrial R&D settings.
• Peptidomimetic Development: The carboxy-methylethylamino group makes it suitable for creating peptide analogs and mimetics with improved pharmacokinetic profiles.

Basic Information

Product Name	4-[(1-Carboxy-1-Methylethyl)Amino]-2-Fluorobenzoic Acid
CAS No.	1332524-02-3
Molecular Formula	C11H12FNO4
Molecular Weight	241.22 g/mol
Synonyms	2-Fluoro-4-[(2-methyl-1,1-dicarboxyethyl)amino]benzoic Acid; 4-(1-Carboxy-1-methylethylamino)-2-fluorobenzoic Acid; 2-Fluoro-4-[(1-carboxy-1-methylethyl)amino]benzoic Acid; 4-(2-Carboxypropan-2-ylamino)-2-fluorobenzoic Acid; 2-Fluoro-4-[(2-carboxypropan-2-yl)amino]benzoic Acid; 4-Amino-2-fluorobenzoic Acid N-(1,1-dimethyl-2,2-dicarboxyethyl) Derivative; API Intermediate 1332524-02-3
EINECS	Contact for details

Quality Control

Our 4-[(1-Carboxy-1-Methylethyl)Amino]-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance documentation for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.