Description

4-[(Cyclopropylcarbonyl)Amino]-3-Fluorobenzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzoic acid derivative structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with improved efficacy and selectivity.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in biochemical assays and target identification studies.
• Material Science: A potential monomer or additive for creating specialty polymers with unique thermal or chemical resistance properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	4-[(Cyclopropylcarbonyl)Amino]-3-Fluorobenzoic Acid
CAS No.	1314406-43-3
Molecular Formula	C11H10FNO3
Molecular Weight	223.20 g/mol
Synonyms	3-Fluoro-4-[(cyclopropylcarbonyl)amino]benzoic acid; 4-(Cyclopropanecarboxamido)-3-fluorobenzoic acid; 4-(Cyclopropylcarboxamido)-3-fluorobenzoic Acid; Benzoic acid, 4-[(cyclopropylcarbonyl)amino]-3-fluoro-; 1314406-43-3; 4-Cyclopropylcarboxamido-3-fluorobenzoic acid; 4-(N-Cyclopropanecarboxamido)-3-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-[(Cyclopropylcarbonyl)Amino]-3-Fluorobenzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.