Description

5-Fluorobenzofuran-6-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the introduction of fluorine to modulate biological activity, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the benzofuran scaffold and fluorine atom enhance efficacy and environmental profile.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed as a building block for designing activity-based probes and molecular tags to study biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	5-Fluorobenzofuran-6-Carboxylic Acid
CAS No.	1312556-72-1
Molecular Formula	C9H5FO3
Molecular Weight	180.13 g/mol
Synonyms	6-Carboxy-5-fluorobenzofuran; 5-Fluoro-6-benzofurancarboxylic Acid; 5-Fluoro-1-benzofuran-6-carboxylic acid; 5-Fluoro-benzofuran-6-carboxylic acid; 5-Fluorobenzofuran-6-carboxylic acid; 1312556-72-1; 5-Fluoro-6-carboxybenzofuran
EINECS	Contact for details

Quality Control

Our 5-Fluorobenzofuran-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP (current Good Manufacturing Practice) requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.