Description

Mglu2 Agonist CAS NO 1311385-32-6 is a high-purity, small-molecule compound designed for advanced research and development in neuroscience. This compound is a potent and selective agonist for the metabotropic glutamate receptor subtype 2 (mGlu2), making it a critical tool for investigating neurological pathways and potential therapeutic targets. It is essential for pharmaceutical researchers, medicinal chemists, and academic institutions focused on CNS disorders, neuropharmacology, and drug discovery programs.

Application

• Neuroscience Research: A key pharmacological tool for studying the role of mGlu2 receptors in synaptic transmission, plasticity, and neural circuit function.
• Drug Discovery & Preclinical Studies: Used in high-throughput screening (HTS), target validation, and lead optimization for CNS-targeted therapeutics.
• Mechanism of Action (MoA) Studies: Enables detailed investigation into receptor signaling pathways, allosteric modulation, and downstream cellular effects.
• Academic & Institutional Research: Supports fundamental research in universities and institutes exploring anxiety, schizophrenia, depression, and other neurological conditions.
• Biochemical Assay Development: Serves as a reference standard in developing and validating functional assays (e.g., calcium flux, cAMP inhibition) for mGlu2 receptor activity.
• Comparative Pharmacology: Used to evaluate selectivity and efficacy against other mGlu receptor subtypes and related GPCR targets.

Basic Information

Item	Detail
Product Name	Mglu2 Agonist
CAS No.	1311385-32-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	mGlu2 Receptor Agonist; Metabotropic Glutamate Receptor 2 Agonist; 1311385-32-6; LY-2812223; (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid; Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)-; Agonist for mGluR2
EINECS	Contact for details

Quality Control

Our Mglu2 Agonist is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We adhere to industry best practices to support your regulatory and compliance needs in preclinical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.