Description

5-Propargyloxy-Du Cep is a high-purity, specialized chemical intermediate featuring a propargyl ether functional group attached to a cephalosporin-derived core structure. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel antibiotic candidates and targeted drug conjugates. It serves as a key building block for medicinal chemists and R&D teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the research and synthesis of new cephalosporin-based antibiotics and β-lactam derivatives.
• Click Chemistry Reagent: Utilizes the alkyne (propargyl) group for Huisgen cycloaddition (click chemistry) reactions to create bioconjugates or label biomolecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize antimicrobial potency and pharmacokinetic properties.
• API Development: Employed in the development and scale-up processes for active pharmaceutical ingredients (APIs) with enhanced efficacy.
• Bioconjugation: Used to attach cephalosporin moieties to antibodies, proteins, or other drug delivery platforms for targeted therapy.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex organic molecules in custom synthesis and contract manufacturing.

Basic Information

Product Name	5-Propargyloxy-Du Cep
CAS No.	1311144-61-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-Propargyloxy DuCep; DuCep Propargyl Ether; 7β-[(2-Amino-2-carboxyethyl)thio]-3-[(propargyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (Derivative); Cephalosporin Propargyl Ether Intermediate; Propargyloxy Cephalosporin Derivative; Antibiotic Synthesis Intermediate
EINECS	Contact for details

Quality Control

Every batch of 5-Propargyloxy-Du Cep is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are developed with research-grade and potential GMP standards in mind, suitable for critical pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when necessary to prevent oxidation and moisture uptake. Keep the container sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.