Description

2-(4-Acetylphenyl)-2,2-Difluoroacetic Acid is a high-purity, specialty fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a difluoroacetate moiety and an acetylphenyl group, makes it a versatile precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from the stability and bioactivity of fluorinated compounds.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules in electronic display applications.
• Advanced Polymer Modification: Incorporated as a monomer or modifier to introduce fluorine atoms into polymer backbones, enhancing chemical resistance and thermal stability.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination methodologies and creating novel chemical libraries.
• Complex Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and material science.

Basic Information

Product Name	2-(4-Acetylphenyl)-2,2-Difluoroacetic Acid
CAS No.	1308915-16-3
Molecular Formula	C10H8F2O3
Molecular Weight	214.17 g/mol
Synonyms	2,2-Difluoro-2-(4-acetylphenyl)acetic Acid; 4-Acetyl-α,α-difluorophenylacetic Acid; 2-(4-Acetylphenyl)-2,2-difluoroethanoic Acid; [4-(Difluoroacetyl)phenyl]acetic Acid (tautomeric form); 4-Acetylbenzeneacetic Acid, 2,2-difluoro-; 1308915-16-3; p-Acetyl-α,α-difluorophenylacetic Acid
EINECS	Contact for details

Quality Control

Our production of 2-(4-Acetylphenyl)-2,2-Difluoroacetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its acid nature, ensure storage containers are made of compatible materials (e.g., glass, fluoropolymer-lined).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.