Description

1,3-Benzodioxole-5-Carboxylic Acid, 2,2-Difluoro-7-Hydroxy-, Methyl Ester is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a benzodioxole core and difluoro-hydroxy substitution, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced organic materials requiring specific fluorinated motifs.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1,3-Benzodioxole-5-Carboxylic Acid, 2,2-Difluoro-7-Hydroxy-, Methyl Ester
CAS No.	1298047-57-0
Molecular Formula	C10H8F2O5
Molecular Weight	246.16 g/mol
Synonyms	2,2-Difluoro-7-hydroxy-1,3-benzodioxole-5-carboxylic acid methyl ester; Methyl 2,2-difluoro-7-hydroxy-1,3-benzodioxole-5-carboxylate; 2,2-Difluoro-7-hydroxybenzo[1,3]dioxole-5-carboxylic acid methyl ester; 5-(Methoxycarbonyl)-2,2-difluoro-7-hydroxy-1,3-benzodioxole; Difluorohydroxybenzodioxole methyl carboxylate
EINECS	Contact for details

Quality Control

Every batch of our 1,3-Benzodioxole-5-Carboxylic Acid, 2,2-Difluoro-7-Hydroxy-, Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.