Description

3-Fluoro-2-(Pyrimidin-2-Yl)Benzoic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a benzoic acid core with fluorine and pyrimidine substituents, enabling precise molecular design. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a versatile scaffold for creating complex ligands in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Organic Electronic Materials: A potential building block for novel organic semiconductors and light-emitting materials due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and scale-up development.

Basic Information

Product Name	3-Fluoro-2-(Pyrimidin-2-Yl)Benzoic Acid
CAS No.	1293285-04-7
Molecular Formula	C₁₁H₇FN₂O₂
Molecular Weight	218.19 g/mol
Synonyms	3-Fluoro-2-(pyrimidin-2-yl)benzoic acid; 2-Pyrimidin-2-yl-3-fluorobenzoic acid; Benzoic acid, 3-fluoro-2-(2-pyrimidinyl)-; 3-Fluoro-2-(2-pyrimidinyl)benzoic acid; 1293285-04-7; 3-Fluoro-2-pyrimidin-2-ylbenzoic acid; 3-Fluoro-2-(2-pyrimidyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Pyrimidin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.