Description

Methyl 2-Fluoro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions to construct complex fluorinated aromatic systems. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to create fluorinated aromatic segments in the development of advanced herbicides, fungicides, and pesticides with enhanced properties.
• Material Science Research: Building block for constructing fluorinated organic frameworks, liquid crystals, and polymers with specific electronic or optical characteristics.
• Chemical Biology & Diagnostics: Employed in the synthesis of fluorinated probes, tags, and molecular tools for imaging and biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research laboratories for bespoke synthesis projects requiring precise fluorinated boronic ester chemistry.

Basic Information

Product Name	Methyl 2-Fluoro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1293284-61-3
Molecular Formula	C14H18BFO4
Molecular Weight	280.10 g/mol
Synonyms	2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Fluoro-6-(pinacolatoboron)benzoic acid methyl ester; Methyl 6-borono-2-fluorobenzoate pinacol ester; 1293284-61-3; Methyl 2-fluoro-6-pinacolatoboronbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.