Description

5-Fluoro-2-(Pyrimidin-2-Yl)Benzoic Acid CAS NO 1293284-57-7 is a high-purity, heterocyclic benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a fluorinated aromatic ring and a pyrimidine moiety, makes it a valuable scaffold for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Investigated for the creation of novel organic electronic materials and metal-organic frameworks (MOFs).
• Biochemical Tool Compound: Utilized in life science research as a probe or inhibitor to study specific enzymatic pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Fluoro-2-(Pyrimidin-2-Yl)Benzoic Acid
CAS No.	1293284-57-7
Molecular Formula	C₁₁H₇FN₂O₂
Molecular Weight	218.19 g/mol
Synonyms	5-Fluoro-2-(2-pyrimidinyl)benzoic acid; 2-(Pyrimidin-2-yl)-5-fluorobenzoic acid; Benzoic acid, 5-fluoro-2-(2-pyrimidinyl)-; 1293284-57-7; 5-Fluoro-2-pyrimidin-2-ylbenzoic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Pyrimidin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.