Description

3-Fluoro-4-(2-Methylphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique structural combination of a benzoic acid core with fluorine and an ortho-methylphenyl substituent, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies (LCDs), where it helps fine-tune dielectric anisotropy and viscosity.
• Organic Electronic Materials: Employed in the development of organic semiconductors, charge-transport materials, and non-linear optical (NLO) materials due to its conjugated system and electron-withdrawing groups.
• Chemical Research & Development: A versatile scaffold for academic and industrial research in organic synthesis, catalysis, and the development of novel fluorinated compounds.
• Complex Ligand Synthesis: Used to create specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging the carboxylic acid group for coordination.

Basic Information

Product Name	3-Fluoro-4-(2-Methylphenyl)Benzoic Acid
CAS No.	1284813-06-4
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	3-Fluoro-4-(o-tolyl)benzoic acid; 4-(2-Methylphenyl)-3-fluorobenzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-2-methyl-; 3'-Fluoro-2-methyl[1,1'-biphenyl]-3-carboxylic acid; 3-Fluoro-4-(2-methylphenyl)benzoic acid; Benzoic acid, 3-fluoro-4-(2-methylphenyl)-; 2-Methyl-3'-fluorobiphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(2-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.