Description

2-Fluoro-4-(1H-Tetrazol-5-Yl)Benzoic Acid is a high-value, multifunctional heterocyclic building block that combines a benzoic acid core with both fluorine and tetrazole substituents. This unique structure makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the life sciences sector for its role in creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for creating molecules with enhanced metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the tetrazole moiety can act as a bioisostere for carboxylic acids.
• Material Science Research: Serves as a precursor for designing specialty polymers, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and other tools used in biochemical research.
• Coordination Chemistry: The tetrazole and carboxylic acid groups make it a versatile ligand for complexing various metal ions in catalytic systems.

Basic Information

Item	Detail
Product Name	2-Fluoro-4-(1H-Tetrazol-5-Yl)Benzoic Acid
CAS No.	1281983-77-4
Molecular Formula	C8H5FN4O2
Molecular Weight	208.15 g/mol
Synonyms	5-(3-Fluoro-4-carboxyphenyl)-1H-tetrazole; 4-(1H-Tetrazol-5-yl)-2-fluorobenzoic Acid; 2-Fluoro-4-(2H-tetrazol-5-yl)benzoic acid; 2-Fluoro-4-(tetrazol-5-yl)benzoic acid; 2-Fluoro-4-(1H-1,2,3,4-tetrazol-5-yl)benzoic acid; Benzoic acid, 2-fluoro-4-(1H-tetrazol-5-yl)-; FTBA (abbreviation)
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-4-(1H-Tetrazol-5-Yl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.