Description

4'-Fluoro-3'-Nitrobiphenyl-3-Carboxylic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which incorporates both a carboxylic acid and a nitro-fluoro substituted biphenyl system, enabling precise structural modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require sophisticated building blocks for drug discovery and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the biphenyl core and fluorine atom contribute to biological activity and environmental stability.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, such as semiconductors and liquid crystals, due to its conjugated aromatic structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	4'-Fluoro-3'-Nitrobiphenyl-3-Carboxylic Acid
CAS No.	1280786-72-2
Molecular Formula	C₁₃H₈FNO₄
Molecular Weight	261.21 g/mol
Synonyms	3'-Nitro-4'-fluorobiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-fluoro-3'-nitro-; 4'-Fluoro-3'-nitro[1,1'-biphenyl]-3-carboxylic acid; 3-Carboxy-4'-fluoro-3'-nitrobiphenyl; 4-Fluoro-3-nitrobiphenyl-3'-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-3'-Nitrobiphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.