Description

Methyl 6-Fluoro-3-Oxo-2,3-Dihydro-1H-Indene-5-Carboxylate is a high-purity fluorinated indanone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular scaffold, which is designed for the efficient construction of complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the biological activity of the fluorinated indanone core.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialized polymers and organic electronic materials with tailored properties.
• Academic & R&D Laboratories: Employed in methodological studies, catalysis research, and as a standard for analytical method development in fluorinated compound analysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines for clinical trial materials.

Basic Information

Product Name	Methyl 6-Fluoro-3-Oxo-2,3-Dihydro-1H-Indene-5-Carboxylate
CAS No.	1273651-10-7
Molecular Formula	C11H9FO3
Molecular Weight	208.19 g/mol
Synonyms	6-Fluoro-3-oxo-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester; Methyl 6-fluoro-3-oxo-2,3-dihydro-1H-indene-5-carboxylate; 5-Methoxycarbonyl-6-fluoro-1-indanone; 6-Fluoro-5-(methoxycarbonyl)-1-indanone; 1H-Indene-5-carboxylic acid, 6-fluoro-2,3-dihydro-3-oxo-, methyl ester; 1273651-10-7
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Fluoro-3-Oxo-2,3-Dihydro-1H-Indene-5-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our facilities and processes are designed to support development under ICH guidelines, ensuring suitability for research and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.