Description

2,2-Dimethyl-3-[3-(Trifluoromethyl)Phenyl]Propanoic Acid is a high-value, synthetically versatile organic acid featuring a trifluoromethylphenyl group. This compound is a critical pharmaceutical intermediate and building block in advanced organic synthesis, prized for its ability to impart unique physicochemical properties to target molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty monomers and polymers with tailored properties for high-performance materials.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	2,2-Dimethyl-3-[3-(Trifluoromethyl)Phenyl]Propanoic Acid
CAS No.	1271556-64-9
Molecular Formula	C12H13F3O2
Molecular Weight	246.23 g/mol
Synonyms	3-(3-(Trifluoromethyl)phenyl)-2,2-dimethylpropanoic acid; 2,2-Dimethyl-3-(3-trifluoromethylphenyl)propionic acid; α,α-Dimethyl-3-(trifluoromethyl)hydrocinnamic acid; 3-[3-(Trifluoromethyl)phenyl]-2,2-dimethylpropanoic acid; 2,2-Dimethyl-3-(m-trifluoromethylphenyl)propanoic acid; DTMPA; CAS 1271556-64-9
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3-[3-(Trifluoromethyl)Phenyl]Propanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.