Description

Pentanoic Acid, 5-[[3-(11,12-Didehydrodibenz[B,F]Azocin-5(6H)-Yl)-3-Oxopropyl]Amino]-5-Oxo-, 2,5-Dioxo-1-Pyrrolidinyl Ester is a specialized, high-purity chemical intermediate featuring a reactive N-hydroxysuccinimide (NHS) ester group. This compound is designed for efficient bioconjugation and peptide synthesis, enabling the formation of stable amide bonds under mild aqueous conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates, particularly for targeted therapies.
• Bioconjugation Reagent: Used to covalently link proteins, antibodies, or peptides to other molecules such as drugs, fluorophores, or solid supports for diagnostic and therapeutic applications.
• Peptide Synthesis: Facilitates the coupling of amino acids and peptide fragments in solid-phase and solution-phase peptide synthesis.
• Proteomics Research: Employed in chemical proteomics for labeling and enriching specific proteins or studying protein-protein interactions.
• ADC (Antibody-Drug Conjugate) Development: Serves as a critical linker-payload component in the construction of next-generation ADCs for oncology.
• Material Science: Used to functionalize surfaces and polymers for biomedical devices and biosensors.

Basic Information

Product Name	Pentanoic Acid, 5-[[3-(11,12-Didehydrodibenz[B,F]Azocin-5(6H)-Yl)-3-Oxopropyl]Amino]-5-Oxo-, 2,5-Dioxo-1-Pyrrolidinyl Ester
CAS No.	1269997-07-0
Molecular Formula	C28H27N3O6
Molecular Weight	501.53 g/mol
Synonyms	5-[[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]amino]-5-oxopentanoic acid 2,5-dioxo-1-pyrrolidinyl ester; NHS Ester of Dibenzoazocine Derivative; N-Succinimidyl Ester Intermediate; CAS 1269997-07-0; Bioconjugation Linker; Reactive Ester for Peptide Coupling; Dibenzo[b,f]azocine-5(6H)-propanoic acid, 11,12-didehydro-, 2,5-dioxo-1-pyrrolidinyl ester, 5-(aminocarbonyl)pentanoate
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 5-[[3-(11,12-Didehydrodibenz[B,F]Azocin-5(6H)-Yl)-3-Oxopropyl]Amino]-5-Oxo-, 2,5-Dioxo-1-Pyrrolidinyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, freezer. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.