Description

2-(4-(Trifluoromethyl)Benzyl)Butanoic Acid is a high-value fluorinated organic building block characterized by its unique combination of a butanoic acid chain and a trifluoromethyl-substituted benzyl group. This structure makes it a critical intermediate for synthesizing advanced molecules with enhanced metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers for advanced material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting inflammation, CNS disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modifiers: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex fluorinated compounds.
• Ligand & Catalyst Development: Used to construct sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	2-(4-(Trifluoromethyl)Benzyl)Butanoic Acid
CAS No.	1269529-72-7
Molecular Formula	C12H13F3O2
Molecular Weight	246.23 g/mol
Synonyms	2-[(4-(Trifluoromethyl)phenyl)methyl]butanoic acid; α-(4-Trifluoromethylbenzyl)butyric Acid; 4-(Trifluoromethyl)benzylbutanoic Acid; 2-((4-(Trifluoromethyl)benzyl))butanoic Acid; Butanoic acid, 2-[(4-(trifluoromethyl)phenyl)methyl]-; 2-(4-Trifluoromethylbenzyl)butyric Acid; 2-(p-Trifluoromethylbenzyl)butanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(4-(Trifluoromethyl)Benzyl)Butanoic Acid is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood or with adequate local exhaust ventilation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.