Description

Methyl 3-Amino-2-Chloro-6-Fluorobenzoate is a high-purity, multi-functional aromatic ester building block of significant importance in advanced organic synthesis. Its unique substitution pattern, featuring amino, chloro, and fluoro groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 3-Amino-2-Chloro-6-Fluorobenzoate
CAS No.	1268830-74-5
Molecular Formula	C8H7ClFNO2
Molecular Weight	203.60 g/mol
Synonyms	Benzoic acid, 3-amino-2-chloro-6-fluoro-, methyl ester; Methyl 3-amino-2-chloro-6-fluorobenzoate; 2-Chloro-6-fluoro-3-aminobenzoic acid methyl ester; 3-Amino-2-chloro-6-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-2-Chloro-6-Fluorobenzoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.