Description

5-Chloro-2-Fluoro-4-Methylbenzoic Acid is a high-purity, multi-functional benzoic acid derivative serving as a critical building block in advanced chemical synthesis. Its value lies in the strategic positioning of halogen and methyl substituents on the aromatic ring, which enables precise structural modifications and the introduction of specific physicochemical properties into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new small-molecule drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the benzoic acid scaffold is a common motif.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized organic compounds used in electronic displays and photonic devices.
• Organic Ligand & Catalyst Development: The carboxylic acid functionality allows it to be used in constructing complex ligands for metal-organic frameworks (MOFs) or homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical companies for bespoke synthesis projects requiring halogenated benzoic acid derivatives.
• Academic & Industrial Research: A valuable reagent for probing structure-activity relationships (SAR) and developing new synthetic methodologies in organic chemistry.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methylbenzoic Acid
CAS No.	1263274-67-4
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	4-Methyl-5-chloro-2-fluorobenzoic Acid; 2-Fluoro-5-chloro-4-methylbenzoic Acid; Benzoic acid, 5-chloro-2-fluoro-4-methyl-; 5-Chloro-2-fluoro-p-toluic Acid
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-Fluoro-4-Methylbenzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We operate under a quality management system and can support projects requiring GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.