Description

tert-Butyl 3-Bromo-5-Fluorobenzoate is a high-purity, synthetically valuable benzoate ester derivative. This compound serves as a critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that require halogenated benzoate motifs.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Serves as a starting point for synthesizing fluorinated molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Detail
Product Name	tert-Butyl 3-Bromo-5-Fluorobenzoate
CAS No.	1262834-57-0
Molecular Formula	C11H12BrFO2
Molecular Weight	275.12 g/mol
Synonyms	3-Bromo-5-fluorobenzoic acid tert-butyl ester; tert-Butyl 3-bromo-5-fluorobenzoate; Benzoic acid, 3-bromo-5-fluoro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-bromo-5-fluorobenzoate; 3-Bromo-5-fluorobenzoic acid 1,1-dimethylethyl ester; t-Butyl 3-bromo-5-fluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 3-Bromo-5-Fluorobenzoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.