Description

4-Fluoro-3-(2-Hydroxymethylphenyl)Benzoic Acid is a high-value fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a benzylic alcohol group on a fluorinated aromatic scaffold, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal & OLED Material Research: Serves as a versatile building block for creating fluorinated aromatic cores in advanced electronic and display materials.
• Complex Ligand & Catalyst Development: The carboxylic acid and alcohol functionalities allow for chelation and modification, useful in designing novel catalysts for asymmetric synthesis.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, potentially improving chemical resistance, thermal stability, and surface properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in cross-coupling and fluorination chemistry research.

Basic Information

Product Name	4-Fluoro-3-(2-Hydroxymethylphenyl)Benzoic Acid
CAS No.	1262011-07-3
Molecular Formula	C14H11FO3
Molecular Weight	246.23 g/mol
Synonyms	3-(2-(Hydroxymethyl)phenyl)-4-fluorobenzoic Acid; 4-Fluoro-3-(2-(hydroxymethyl)phenyl)benzoic Acid; Benzoic acid, 4-fluoro-3-[2-(hydroxymethyl)phenyl]-; [2-(4-Fluoro-3-carboxyphenyl)phenyl]methanol
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(2-Hydroxymethylphenyl)Benzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.