Description

4'-Fluoro-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-value, multi-functional biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, central nervous system (CNS), and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorine-containing liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its conjugated biphenyl core.
• Chemical Research: Utilized as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Polymer Modifier: Can be incorporated as a monomer or additive to alter the surface properties and stability of high-performance polymers.

Basic Information

Product Name	4'-Fluoro-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1262010-56-9
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	3'-Fluoro-4'-(trifluoromethyl)biphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-fluoro-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-4'-fluorobiphenyl-3-carboxylic acid; 4'-Fluoro-5-trifluoromethylbiphenyl-3-carboxylic acid; 3-Carboxy-4'-fluoro-5-trifluoromethylbiphenyl; Biphenyl-3-carboxylic acid, 4'-fluoro-5-(trifluoromethyl)- derivative
EINECS	Contact for details

Quality Control

Every batch of 4'-Fluoro-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.