Description

2'-Chloro-2-Fluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity biphenyl derivative carboxylic acid, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its precise molecular architecture, which is essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated biphenyl core.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated biphenyl-based compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for synthesizing specialized organic semiconductors and charge transport materials.
• Chemical Research: Employed in academic and industrial R&D for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Material Science: Utilized in the development of advanced polymers and ligands for catalysis with tailored properties.

Basic Information

Product Name	2'-Chloro-2-Fluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1262008-90-1
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	2'-Chloro-2-fluoro-4'-methylbiphenyl-4-carboxylic acid; 4'-Methyl-2'-chloro-2-fluorobiphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 2'-chloro-2-fluoro-4'-methyl-; 2-Chloro-2'-fluoro-4-methylbiphenyl-4'-carboxylic acid; 2-Fluoro-2'-chloro-4'-methylbiphenyl-4-carboxylic acid; Biphenyl-4-carboxylic acid derivative (CAS 1262008-90-1)
EINECS	Contact for details

Quality Control

Our 2'-Chloro-2-Fluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.