Description

2-Chloro-4-(2,6-Difluorophenyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and fluorinated structure makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its rigid, halogenated aromatic core.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Fundamental research compound in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Chloro-4-(2,6-Difluorophenyl)Benzoic Acid
CAS No.	1262006-10-9
Molecular Formula	C13H7ClF2O2
Molecular Weight	268.64 g/mol
Synonyms	2-Chloro-4-(2,6-difluorophenyl)benzoic acid; Benzoic acid, 2-chloro-4-(2,6-difluorophenyl)-; 4-(2,6-Difluorophenyl)-2-chlorobenzoic Acid; 2-Chloro-4-(2,6-difluorobenzene)benzoic Acid; (2-Chloro-4-(2,6-difluorophenyl)phenyl)formic Acid; 1262006-10-9 (CAS); 2-Cl-4-(2,6-F2-Ph)BA (Abbreviation)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(2,6-Difluorophenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.