Description

2,3',5'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative, a key building block in advanced organic synthesis. Its trifluorinated biphenyl core offers unique electronic and steric properties, making it an essential intermediate for creating complex molecules with enhanced stability and bioactivity. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve metabolic stability and membrane permeability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Material Science: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.

Basic Information

Product Name	2,3',5'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1262006-03-0
Molecular Formula	C13H7F3O2
Molecular Weight	252.19 g/mol
Synonyms	2,3',5'-Trifluorobiphenyl-4-carboxylic Acid; [1,1'-Biphenyl]-4-carboxylic Acid, 2,3',5'-trifluoro-; 4-Carboxy-2,3',5'-trifluorobiphenyl; 2,3',5'-Trifluoro-4-biphenylcarboxylic Acid; 2,3',5'-Trifluoro-4-phenylbenzoic Acid; 2,3',5'-Trifluoro-4'-carboxybiphenyl; (2,3',5'-Trifluorobiphenyl-4-yl)carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2,3',5'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical data are provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.