Description

3-(3-Chlorophenyl)-4-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, is engineered to impart specific electronic and steric properties essential for developing active compounds. This product is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel drugs, crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a versatile synthon in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its reactive carboxylic acid group and halogenated aromatic ring.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex molecules for clients in the life sciences sector.

Basic Information

Product Name	3-(3-Chlorophenyl)-4-Fluorobenzoic Acid
CAS No.	1262005-93-5
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	4-Fluoro-3-(3-chlorophenyl)benzoic Acid; 3-(3-Chlorophenyl)-4-fluorobenzoic Acid; Benzoic acid, 4-fluoro-3-(3-chlorophenyl)-; 3'-Chloro-4-fluorobiphenyl-3-carboxylic Acid; 4-Fluoro-3-(3-chlorophenyl)benzoic acid; 3-(3-Chlorophenyl)-4-fluoro-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.